My wife brushes/flosses regularly and mints-even Altoids-or mouthwashes do not work.

There may be so many reasons behind it. The first one may be of dental or gum problem. So you have to consult a Dentist for that. If the problem still persists, find out if the digestion is quite ok if not you have to consult a good Doctor for digestion problem and have to change your food styles. Better exercise is a must for such problems. Get teetch brushed after every meals. Problem may of ENT nature, so you also consult an ENT doctor for his advice. I hope you will get through and will love when your spouse will smile. Never forget God has made us to be happy and healthy so go ahead and win the challenge before you. I hope one day you will write on this forum that you met the challenge and won the proiblem.